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    Ventolin is a reliever medication for asthma delivered in a Metered Dose Inhaler or MDI, and globally it is one of the most commonly used treatments for any medical condition. I am not dependent on it as I used to be, as I now take a new generation MDI combining reliever and preventer asthma medications, but Ventolin is a useful backup. Asthma can be fatal and I personally know of several people who have died of attacks. Hence the ongoing international drive for more effective medications. It can be a wheezy or shallow fast breath though constricted airways in the lungs. The tubes have reacted to some trigger by tightening and producing mucus, leaving less room for the passage of air. The causes of asthma are numerous and person-specific, from allergens to a change in atmospheric pressure. It can become a battle to breathe, with the out-breath often harder to perform than the in-breath. A research team headed by Chinese scientists has developed a potentially groundbreaking treatment for asthma, a respiratory disease affecting some 235 million people worldwide. For more than eight months, researchers from four Chinese institutes and two U. universities tested over 6,000 drugs, eventually narrowing the field down to one: TSG12, which activates a protein that causes the smooth muscle cells of the throat to relax during an asthma attack. The scientists first tested the drug on mouse models, and later on human smooth muscle cells. Their paper was published Thursday in Science Translational Medicine, an interdisciplinary journal under Science. Characterized by symptoms such as wheezing, coughing, and difficulty breathing, asthma is a chronic and potentially fatal lung disorder that disproportionately affects children. Allergens, pollutants, cold air, and other factors can trigger asthma attacks. S., around half of all people with asthma experience an attack at least once a year, resulting in over 2 million trips to emergency rooms and 500,000 hospital stays. Because there is no cure, people with the disorder rely on a combination of drugs — mainly bronchodilators and steroids — administered via inhalers to keep the symptoms in check. The asthma rate in China, meanwhile, has grown considerably in the past decade, and over 70 percent of urban dwellers affected struggle to keep their symptoms under control, according to research conducted by the China Asthma Research Group, a cohort of over 100 experts from 30 Chinese hospitals.

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    Now that months have passed and I’m basking in our summer sun, I can safely confess that I had a miserably unhealthy winter. It started in November with my first ever broken bone, a silly bike-vs-oil-patch accident which broke my clavicle and brought me surprisingly distressing pain for more than a month. But far worse was when I was diagnosed with asthma last December and needed two inhalers to breathe better. It started insidiously, when I began to wake up deep in the night with achy chest pains. I initially thought it was just rib bruising from my bike tumble, but then I also started feeling short of breath. One morning I woke up suddenly gasping for air, and I finally went to a colleague at my clinic. My chest x-ray was normal but I took a breathing test which showed my lung function only 60% of normal, and she said I probably had asthma. And while I was incredibly relieved to feel better, I was shocked and disturbed by my diagnosis. This server could not verify that you are authorized to access the document requested. Either you supplied the wrong credentials (e.g., bad password), or your browser doesn't understand how to supply the credentials required.

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