She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Can plaquenil cause skin pigment to darken Plaquenil makes me tired The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and Jun 13, 2019 Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. Barbara L Roque, MD, DPBO, FPAO is a member of the following medical societies American Academy of Ophthalmology, American Association for Pediatric Ophthalmology and Strabismus, Philippine Academy of Ophthalmology, Philippine Society of Cataract and Refractive Surgery, Philippine Society of Pediatric Ophthalmology and Strabismus Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Hydroxychloroquine american academy of ophthalmology Chloroquine and Hydroxychloroquine Toxicity Workup Approach., What Is Plaquenil? - American Academy of Ophthalmology Hydroxychloroquine-o-acetateChloroquine thailand malaria Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Chloroquine and Hydroxychloroquine Toxicity Practice.. Hydroxychloroquine Do We All See Eye to Eye? a Single-Site.. Hydroxychloroquine maculopathy. a. Early hydroxychloroquine maculopathy. There is a parafoveal ring of hyperautofluorescence green arrows. b. Hydroxychloroquine maculopathy with atrophy. There is a bull’s-eye pattern of hypoautofluorescence yellow arrows corresponding to parafoveal atrophy on the optical coherence tomography OCT B-scan. c. Background. The American Academy of Ophthalmology recommendations for screening of chloroquine CQ and hydroxychloroquine HCQ retinopathy were published in 2002, but improved screening tools and new knowledge about the prevalence of toxicity have appeared in the ensuing years. In 2011, an American Academy of Ophthalmology committee published revised guidelines concerning screening for hydroxychloroquine toxicity. 1 Previous guidelines had been published in 2002. guidelines recommend a baseline examination at onset of therapy that should include macular static perimetry eg, the Humphrey 10-2 visual field 10-2 VF and at least 1 of multifocal.