This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. What is the filler in hydroxychloroquine Chloroquine toxicity dose Chloroquine hcc Plaquenil during surgery Chloroquine, an Antifungal but Also a Fertility Drug Lodewyk Kock, Chantel Swart, and Carolina Pohl Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, Bloemfontein, South Africa Malaria affects the reproductive health of both men & women For more articles on diseases & conditions, visit our diseases & conditions section. Chloroquine effected a dose-related reduction in fertility of the male rats as evidenced by a reduction in average number of foetuses of cohabited females, although the sperm count in the groups was not significantly different. This suggest that the drug does play an inhibitory role in sperm function. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine and fertility Aralen chloroquine Malaria Drug Side Effects & Dosage, Malaria affects the reproductive health of both men. Manufacturers of plaquenilPlaquenil grid Oct 21, 2015 Chloroquine. Chloroquine appears to have a deleterious effect on sperm quality in vitro and in vivo in animal studies. Little data are available in males, unlike in pregnant women in which there is a large amount of reassuring data. The teratogenic risk related to the use of hydroxychloroquine is very low. Immunosuppressive drugs and fertility. Chloroquine reduces fertilizing capacity of epididyma sperm.. Chinese Scientists Raise Concerns Over Potential Link Between.. Fertility may improve after adopting a gluten-free diet. Certain medications. Testosterone replacement therapy, long-term anabolic steroid use, cancer medications chemotherapy, certain antifungal medications, some ulcer drugs and certain other medications can impair sperm production and decrease male fertility. Safety and efficacy of chloroquine to treat extraintestinal amebiasis have not been established in children. Geriatric Although appropriate studies on the relationship of age to the effects of chloroquine have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of chloroquine in. In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk.