Chloroquine-induced pigmentation

Discussion in 'North West Pharmacy Canada' started by Batler, 15-Mar-2020.

  1. aZipin User

    Chloroquine-induced pigmentation


    In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent.

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    The black pigment was present as discrete droplets or less commonly within green droplets. The green drop- lets were numerous and were present singly or in clumps. The same patient had blue-black pigmen- tation of the ala nasi, dark costal cartilages, and Volume 5 Number 1 July, 1981 Drug- and heavy metal-induced hyperpigmentation 11 Table VI. Hypopigmentation of hair and freckles occurred in a patient receiving chloroquine sulfate therapy. This patient had a severe congenital renal failure that presumably increased plasma and tissue levels of the drug substantially, accounting for the hypopigmentation. Arch Dermatol 1985;164-1166 Hydroxychloroquine-induced pigmentation lesions usually begin after a few months or years of treatment. When we compared our patients with the controls, we found no significant association with the duration of HCQ treatment or with the cumulative dose of HCQ.

    JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Facial Plastic Surgery JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)A, Bluish-green pigmentation on the legs in a patient with systemic lupus erythematosus without lupus lesions at the time of the skin biopsy. Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosus. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended.

    Chloroquine-induced pigmentation

    Chloroquine –Induced Hair Depigmentation - TB Di Giacomo, NYS., Chloroquine-Induced Hypopigmentation of Hair and Freckles.

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  7. The statistical associations of HCQ-induced pigmentation with several variables were calculated using univariate and multivariate analyses. RESULTS Among the 24 patients, skin pigmentation appeared after a median HCQ treatment duration of 6.1 years range, 3 months-22 years.

    • Hydroxychloroquine-induced pigmentation in patients with..
    • Hydroxychloroquine-Induced Pigmentation in Patients With..
    • Drug-Induced Pigmentation Skin and Urine Color Changes.

    Pigmentation to manifestations of systemic illnesses e.g. Addison’s disease and malignant neoplasms e.g. melanoma and Kaposi’s sarcoma. Therefore, an understanding of the causes of mucosal pigmentation and appropriate evaluation of the patient are essential. Oral pigmentation may be exogenous or endogenous in origin. A 16-year-old, blonde-haired patient was evaluated for a new band of lighter-colored hair located approximately 3 cm from the scalp. The patient first noted the change in hair color 1 week after. Drug-induced skin pigmentation is estimated to account for 10-20% of all cases of acquired dyspigmentation worldwide. Race. Drug-induced pigmentary changes can occur in persons of any race, but hypomelanosis is seen more frequently and appears more dramatically in patients with darker-pigmented skin.

     
  8. seamen Guest

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Hydroxychloroquine Side Effects, Dosage, Uses, and More Common and Rare Side Effects for Plaquenil Oral Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus
     
  9. Axelman User

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Chloroquine And Hydroxychloroquine Toxicity - StatPearls. Experts debate hydroxychloroquine dosing guidelines in lupus Hydroxychloroquine Being Over-Dosed with New Guidelines.
     
  10. kompage Guest

    Hydroxychloroquine 200 mg Tablets Generic Plaquenil Hydroxychloroquine 200 mg Tablets Due to the national surge in health related Over-The-Counter ordering, certain OTC products are shipping slower than normal. We will continue to use fair share allocation of OTC product to combat shortages and strive to get orders out in a timely manner.

    HYDROXYCHLOROQUINE SULFATE TABLETS, USP
     
  11. Beton New Member

    Plaquenil and Psoriatic Arthritis - Reviews I, too, have PSA and the spondylitis type. I am currently on Plaquenil for the PSA as it works for my fingers and have been on Sulfasalazine for three weeks and am up to the 2 pills twice a day for the last few days for my SI joint. I work full time and try to get up and walk around or do something physical at least every two hours or I lock up and its ridiculous.

    Plaquenil Hydroxychloroquine MyPsoriasisTeam