In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent. Chloroquine for fish ich How long should i take plaquenil The black pigment was present as discrete droplets or less commonly within green droplets. The green drop- lets were numerous and were present singly or in clumps. The same patient had blue-black pigmen- tation of the ala nasi, dark costal cartilages, and Volume 5 Number 1 July, 1981 Drug- and heavy metal-induced hyperpigmentation 11 Table VI. Hypopigmentation of hair and freckles occurred in a patient receiving chloroquine sulfate therapy. This patient had a severe congenital renal failure that presumably increased plasma and tissue levels of the drug substantially, accounting for the hypopigmentation. Arch Dermatol 1985;164-1166 Hydroxychloroquine-induced pigmentation lesions usually begin after a few months or years of treatment. When we compared our patients with the controls, we found no significant association with the duration of HCQ treatment or with the cumulative dose of HCQ. JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Facial Plastic Surgery JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)A, Bluish-green pigmentation on the legs in a patient with systemic lupus erythematosus without lupus lesions at the time of the skin biopsy. Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosus. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended. Chloroquine-induced pigmentation Chloroquine –Induced Hair Depigmentation - TB Di Giacomo, NYS., Chloroquine-Induced Hypopigmentation of Hair and Freckles. Plaquenil kidney problemsChloroquine chemoprophylaxis defineWhen to switch from plaquenil to methotrexatePlaquenil and difficulty breathingHydroxychloroquine toxic retinopathy The statistical associations of HCQ-induced pigmentation with several variables were calculated using univariate and multivariate analyses. RESULTS Among the 24 patients, skin pigmentation appeared after a median HCQ treatment duration of 6.1 years range, 3 months-22 years. Hydroxychloroquine-induced pigmentation in patients with.. Hydroxychloroquine-Induced Pigmentation in Patients With.. Drug-Induced Pigmentation Skin and Urine Color Changes. Pigmentation to manifestations of systemic illnesses e.g. Addison’s disease and malignant neoplasms e.g. melanoma and Kaposi’s sarcoma. Therefore, an understanding of the causes of mucosal pigmentation and appropriate evaluation of the patient are essential. Oral pigmentation may be exogenous or endogenous in origin. A 16-year-old, blonde-haired patient was evaluated for a new band of lighter-colored hair located approximately 3 cm from the scalp. The patient first noted the change in hair color 1 week after. Drug-induced skin pigmentation is estimated to account for 10-20% of all cases of acquired dyspigmentation worldwide. Race. Drug-induced pigmentary changes can occur in persons of any race, but hypomelanosis is seen more frequently and appears more dramatically in patients with darker-pigmented skin.