Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Combine ibuprofen and hydroxychloroquine Taking plaquenil for lupus Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. This dosing would NOT apply to someone already taking plaquenil, because it has a very long ~ 30 days half-life, and it’s already in your system, so you just keep on keep’n on. This is not intended to be medical advice; this is just a reminder to refill whatever Rx for plaquenil you might already have. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Lupus on plaquenil Plaquenil oral Reviews and User Ratings Effectiveness, Ease., Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil for rheumatoid arthritis pain New research finds that measuring blood levels of the medication hydroxychloroquine Plaquenil in people with lupus may be an effective way to predict risk of retinopathy, a disease which results in impaired or complete loss of vision. The study assessed 537 people with lupus and measured the levels of the drug present in their blood. Study Finds Blood Levels of Plaquenil may be Important Indicator of Eye.. Having lupus, and being on plaquenil. Does that mean I have a.. Plaquenil User Reviews for Systemic Lupus Erythematosus at. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Lupus and Plaquenil research. While Plaquenil was not created with the explicit purpose of helping people minimize the disease activity of lupus, a number of clinical trials have been conducted to examine the clinical impact of the medication. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases.