Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Fies the itching frim plaquenil stop Plaquenil insomnia Quinoric vs plaquenil In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Chronic fatigue is a serious and debilitating condition, and it's often found among those with rheumatoid arthritis. Experts don't entirely understand the relationship between the two, but they have some ideas how they're connected. What is Plaquenil and what are its benefits for Sjögren’s patients? Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can plaquenil cause extreme fatigue Chronic Fatigue From RA 6 Ways to Fight Back Everyday Health, How Rheumatoid Arthritis Triggers Chronic Fatigue Plaquenil medication assistanceChloroquine and proguanil brand nameDoes plaquenil affect the brain fogHow is plaquenil metabolized I also have fatigue and mostly give up social activities in the evening so that I can work most of the day not a quality-of-life choice I like. So I think I will look more closely at these tips from Sarah Sjögrens fatigue – and all autoimmune fatigue – is a clinical conundrum. Sjögrens Fatigue – an Autoimmune Conundrum! SjögrensLife. Ask the Expert Plaquenil and Sjögren’s. Plaquenil for fatigue and pain DailyStrength. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can. My rheumatologist just started me on plaquenil a couple of weeks ago. She said a half-dose - 200 mg because I'm skinny. My fatigue is out of control and ruining my life. I can barely hold on to my job and right after work, I fall asleep, like at 6 PM, then struggle with insomnia all night. Always feel exhausted. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks.