Alternatively, we suggest using this opportunity to take a little break from work and read some of the interesting articles below. Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Plaquenil skin side effects pictures Plaquenil 200mg dosage Another potential mode of action of hydroxychloroquine and chloroquine is interference with cyclic GMP-AMP cGAMP synthase cGAS activity by inhibiting ligand binding 94. The cGAS–stimulator. Hydroxychloroquine is classified as an anti-malarial drug. It is similar to chloroquine Aralen and is useful in treating several forms of malaria as well as lupus erythematosus and rheumatoid arthritis. Its mechanism of action is unknown. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. Hydroxychloroquine mechanism of action Hydroxychloroquine Plaquenil Success, Reviews and Side Effects, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Chloroquine phosphate fish Hydroxychloroquine shares the same mechanism of action as chloroquine, but its more tolerable safety profile makes it the preferred drug to treat malaria and autoimmune conditions. We propose that the immunomodulatory effect of hydroxychloroquine also may be useful in controlling the cytokine storm that occurs late-phase in critically ill SARS. In Vitro Antiviral Activity and Projection of Optimized.. Hydroxychloroquine Plaquenil. Chloroquine and hydroxychloroquine – Knowledge for medical.. Mechanism of Action Immune modulator. Hydroxychloroquine, an alkylated 4-aminoquinoline, is a hydroxylated form of chloroquine and has a biological mechanism of action similar to chloroquine’s. Hydroxychloroquine was originally developed as a safer alternative to chloroquine for the treatment of malaria and was later found to have antirheumatic and anti-inflammatory uses. Hydroxychloroquine HCQ is nearly identical in structure to CQ and has a similar mechanism of action and therapeutic efficacy in rheumatological and infectious diseases. Like CQ, it also has a long half-life, and a very high volume of distribution. Although the precise mechanism of action is unknown, hydroxychloroquine may suppress immune function by interfering with the processing and presentation of antigens and the production of cytokines.