Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine and fluoroquinolone resistance dissertation Does hydroxychloroquine treat fibromyalgia Chloroquine antibacterial activity Here are some of the ways in which Plaquenil is used to control lupus symptoms May prevent lupus flares by as much as 50%. Reduce muscle and joint pain. Reduce lupus related rashes. Protect against pleuritis inflammation of the lining of the lungs. Protect against pericarditis inflammation. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Last week my doc added plaquenil to the mix. I have a pharmacist friend that says it can take up to a year to work, but once its kicks in it can be really good. I suggest you ask your rhuemie for additional help in the meantime. I have had RA going on 12 years, and originally way back when I ws given plaquenil alone and it did nothing. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How does plaquenil work in the body Plaquenil User Reviews for Rheumatoid Arthritis at, Plaquenil - Uses, Side Effects, Interactions - Can plaquenil help osteoarthritis Plaquenil tablets contain the active ingredient hydroxychloroquine, which is a type of medicine called a disease-modifying anti-rheumatic drug DMARD. Unlike painkillers, DMARDs work in rheumatoid arthritis by suppressing the excessive activity of the immune system that causes the inflammation of the joints. Plaquenil hydroxychloroquine. How long did Plaquenil/Hydroxychloroquine take? DailyStrength. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory pathways. For women, start with 100 pounds, and add 5 pounds for every inch over 5 feet. For men, start with 106 pounds, and add 6 pounds for every inch over 5 feet. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight.