For batch specific data refer to the Certificate of Analysis. Tocris products are intended for laboratory research use only, unless stated otherwise. Chloroquine cytotoxic falicparum Plaquenil and gabapentin and famotidine Chloroquine diphosphate is an antimalarial and anti-inflammatory drug widely used to treat malaria and rheumatoid arthritis. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors TLRs. Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances of hypersensitivity reactions which can be accompanied by hepatitis and mild jaundice. Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is a chemotherapeutic agent for the clinical treatment of malaria. Chloroquine is able to bind to DNA, and inhibit DNA replication and RNA synthesis which in turn results in cell death. We invite you to request* or download your copy today! Keywords: Chloroquine diphosphate, Chloroquine diphosphate supplier, Chloroquine, diphosphate, antimalarial, antitumor, antimetastatic, autophagy, apoptosis, Other, Apoptosis, Autophagy, Antimalarials, 4109, Tocris Bioscience $50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image Tocris offers the following scientific literature in this area to showcase our products. Chloroquine solubility in dmso Chloroquine - Cell Signaling Technology, Quinine C20H24O2N2 - PubChem Why take chloroquine phosphate 500 mgPharmacokinetics of chloroquineHydroxychloroquine plaquenil how it workHydroxychloroquine retinalSle plaquenil Compound Name Solvent Solubility mg/mL 2iP Riboside Water TBD Methanol TBD 4-epi-oxytetracycline Water Insoluble DMSO 10 brown solution. Chloroquine phosphate€ Water 100 mM DMSO 1 Ethanol 1 Chlortetracycline HCl€ Water 8.6 Methanol 17.4 Ethanol 1.7 1 M NaOH 50 Choline chloride€ Water 500 Ethanol 28 Compound Name Solvent Solubility mg/mL. Chloroquine diphosphate ≥99%HPLC Selleck ATM/ATR.. Dimethyl sulfoxide reduces. - PubMed Central PMC. Citations are publications that use Tocris products. Selected citations for Chloroquine diphosphate include Tong et al 2018 Corilagin inhibits breast cancer growth via reactive oxygen species-dependent apoptosis and autophagy. Chloroquine is an aminoquinoline that is quinoline which is substituted at position 4 by a 5-diethylaminopentan-2-ylamino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. Chloroquine diphosphate is used as an antimalarial drug and also functions to increase sensitivity of tumor cells to radiation and chemotherapy via inducing autophagy 1. Chloroquine diphosphate has been reported as an adjuvant for radiation and chemotherapy for inducing cell autophagy to anti-cancer cells proliferation or metastasis 2.