MTX monotherapy (MTG) is recommended as (part of) first choice treatment but no head-to-head comparisons are available comparing MTX–HCQ CTG with MTG. RA patients from the Sint Maartenskliniek and Radboudumc Nijmegen who started MTX with or without concomitant HCQ from April 2010 to October 2015 were included. Dose of chloroquine at 4 0 year Chloroquine omeprazole Chloroquine and lysosome ph I have had RA for 10 years and have been on Plaquenil pretty much the whole time. Methotrexate did not work for me and made me very nauseous. I also take 5-10 mg prednisone and an injection of Humira every week. I have had no side effects from the Plaquenil. Prednisone is a mean drug however, I can tell you this as a nurse too but I have to. Was the plaquenil controlling your RA symptoms? The trouble is you lose hair on Methotrexate too. But after losing heaps when I first went on it, I have stabalised now, I have thinner hair but it still looks fine and healthy. If plaq was working for your symptoms I'd go back on it. If you feel like the RA is escallating then go for mtx. Compare Hydroxychloroquine vs. Methotrexate, which is better for uses like RA, Lupus and Arthritis. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Regression modelling was used to correct for confounding. The primary outcome was the between-group ΔDAS28-CRP at 6 months, and secondary outcomes were ΔDAS28-CRP at 12 months, EULAR response at 6 and 12 months, and treatment intensification. Plaquenil vs methotrexate for ra Plaquenil vs. Rheumatrex, Trexall Prescription Treatment for., Methotrexate vs Plaquenil? - How dangerous is hydroxychloroquinePlaquenil eye twitchingPlaquenil chinese translation Sorry to hear that you are having a lot of pain with your RA. I have lupus which mainly affects my joints and skin. I have been taking hydroxychloroquine which is the generic of plaquenil for the past three years. My rheumy recently added Imuran instead of methotrexate. Plaquenil hydroxychloroquine takes up to 3 months to begin working. Arthritis Which would you pick and why? - Plaquenil or.. Compare Hydroxychloroquine vs Methotrexate - Comprehensive.. Member Discussions and Questions Advice Needed. - RA Chicks. My rheumy has officially decided today this is seronegative RA, and its time to start DMARDS to protect my joints. He's giving me a few weeks to do my homework though so that we can choose a medication for this. Basically he wants me to get through the holidays without medication symptoms. He wants me to look at plaquenil and methotrexate. What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. Hydroxychloroquine and sulfasalazine are used for mild. The goal is to minimize both rheumatoid arthritis disease activity and medication side effects. It often takes more than one DMARD to get.