These hard lumps of tissue range in size from about the size of a pea to as large as a ping pong ball. They may develop under the skin over bony areas such as the elbow, ankle, or finger. For some people, treatment with “DMARDs” (disease-modifying antirheumatic drugs) or steroid shots may shrink nodules. Neutropenia hydroxychloroquine Chloroquine phosphate show up on drug test Photosensitivity is a common side-effect of methotrexate, plaquenil, and NSAIDs such as celebrex or advil. Photosensitivity may also be a serious side-effect of anti-TNF drugs such as cimzia, enbrel, humira, remicade, and simponi, as well as sulfasalazine. The symptoms you have depend on what areas of your body the lupus is affecting. But the most common ones include Intense fatigue. Fever. Severe joint pain and muscle aches. Skin rash on the face or body. Extreme sun sensitivity. Weight loss. More in Arthritis. Photosensitivity is a skin reaction i.e. rash that occurs after exposure to ultraviolet UV radiation from the sun or an artificial light source. Photosensitivity can be caused by various agents, including drugs, perfume, cosmetics, and even the sunscreen that is meant to protect your skin. It’s rare, but in some people, nodules are a sign that they have rheumatoid vasculitis, which is inflammation of the small and medium-sized blood vessels. You may need surgery to remove them if they get infected or become painful. Plaquenil photosensitivity rash cheeks Sun allergy - Diagnosis and treatment - Mayo Clinic, Lupus Symptoms Fatigue, Fever, Swollen Lymph Nodes, Rash, & More How long can you stay on plaquenilPlaquenil and cotrimoxazolePlaquenil retinalChikungunya arthritis hydroxychloroquine Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. Hydroxychloroquine DermNet NZ. Photosensitivity Reaction With Certain Medications. Plaquenil Side Effects Common, Severe, Long Term -. There are no specific tests for photosensitivity reactions. A doctor suspects a photosensitivity reaction when a rash appears only in areas exposed to sunlight. A close review of the person's medical history, skin symptoms, any diseases, drugs taken by mouth, or substances applied to the skin such as drugs or cosmetics may help a doctor pinpoint the cause of the photosensitivity reaction. Rashes caused by photosensitivity usually occur on parts of the body that are most often exposed to sun, including the face, neck, ears, and hands. Hats with large brims, along with tightly woven, loose-fitting, long-sleeved shirts and long pants can help provide maximum coverage from the sun. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness.