It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine and malaria Dermatomyositis rash and plaquenil Here we described a non-diabetic patient with RA who developed hypoglycaemia under hydroxychloroquine HCQ treatment. We also discussed the possible mechanisms of hypoglycaemia due to HCQ. A 62-yr-old man was admitted to our hospital with symmetric polyarthritis and morning stiffness for more than 2 h in 2005. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. Hydroxychloroquine HCQ is a commonly used drug for the treatment of systemic lupus erythematosus SLE. Renal involvement is common in SLE. We present a 25-year-old woman with lupus nephritis on peritoneal dialysis whose lupus was quite silent for almost three years, and secondary to HCQ she developed severe hypoglycaemic episodes, which were completely resolved after stopping HCQ. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Hydroxychloroquine hypoglycemia Hydroxychloroquine - an overview ScienceDirect Topics, Hydroxychloroquine Oral Route Precautions - Mayo Clinic Reviews on plaquenil for rheumatoid arthritis Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Hydroxychloroquine-induced hypoglycaemia in non-diabetic.. DailyMed - HYDROXYCHLOROQUINE SULFATE tablet. Hydroxychloroquine HCQ, a commonly used antimalarial drug in rheumatic diseases, has shown favorable metabolic effects on both glucose control and lipid profiles. We describe a case of a young woman with type 1 diabetes whose glycemic control was optimized. Hypoglycemia is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Type 2 diabetes Plaquenil/hydroxychloroquine and hypoglycemia. Julendo posted Hello everyone--I actually have UCTD, not lupus, but my question is about plaquenil so I thought you might be able to answer it. Last week I went to the doctor because I had a bout of food poisoning that was followed by some pretty severe abdominal pain, which is getting better now.