See below for a comprehensive list of adverse effects. Applies to methotrexate: oral solution, oral tablet Other dosage forms: Oral route (Solution) Severe Toxic Reactions, Including Embryo-Fetal Toxicity Methotrexate can cause severe or fatal toxicities. Side effects of hydroxychloroquine weight gain How does plaquenil cause blindness I saw him three weeks ago, and he encouraged me to try to taper down now that the plaquenil is helping so much. According to him, only doses lower than 3 mg per day can be considered to have zero long-term side effects, so he either wants me off the steroids completely, or to get at or below 3 mg. If you are using methotrexate long term, a liver biopsy is usually recommended. Methotrexate use has rarely caused serious sometimes fatal side effects, such as lung problems, lung infections Pneumocystis jiroveci pneumonia, skin reactions, diarrhea, and mouth sores ulcerative stomatitis. See also Side Effects section. Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Methotrexate can cause embryo-fetal toxicity and fetal death. Monitor closely and modify dose or discontinue for the following toxicities: bone marrow suppression, infection, renal, gastrointestinal, hepatic, pulmonary, hypersensitivity and dermatologic. Methotrexate vs plaquenil side effects long term Plaquenil Side Effects Common, Severe, Long Term -, METHOTREXATE - ORAL side effects, medical uses, and drug. Plaquenil for sjogren's syndrome Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Methotrexate vs Plaquenil Comparison -. Methotrexate or Plaquenil? DailyStrength. Re Methotrexate vs Plaquenil side effects long term and short term The MTX dose for autoimmune disease is about 1/1000 the dose they use in cancer patients. MTX also has a long clinical history, which makes it a trustworthy drug, they'll be no "surprise" side effects. We compare the side effects and drug effectiveness of Plaquenil and Methotrexate. The study is created by eHealthMe based on reports of 385,604 people who take Plaquenil and Methotrexate, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Our original studies are referenced on 600+ peer-reviewed medical publications. Methotrexate Rasuvo, Otrexup is a self-injectable solution used to treat psoriasis and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more.