Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine and reduction of metastasis Chloroquine in lupus Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more likely to occur in individuals taking high doses for many years, individuals 60 years or older, or those with significant kidney disease. At the recommended dose, development of visual problems due to the medication is rare. Because ACE inhibitors are metabolized by the kidneys, they do come with a risk of causing kidney damage, especially if you are dehydrated, which is often the case in people with existing kidney problems—like chronic kidney disease. If you are at a higher risk for kidney damage but need an ACE inhibitor. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Is plaquenil safe for one kideny Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., Hydroxychloroquine Plaquenil Plaquenil and lower back painCan hydroxychloroquine 200 mg get you high To make sure hydroxychloroquine is safe for you, tell your doctor if you have a history of vision changes or damage to your retina caused by an anti-malaria medication; heart disease, heart rhythm disorder such as long QT syndrome; diabetes; a stomach disorder; an allergy to quinine; liver or kidney disease; psoriasis; alcoholism; or Plaquenil Hydroxychloroquine Side effects, Images, Uses.. The 10 Worst Medications for Your Kidneys - GoodRx. Will you have Acute kidney failure with Plaquenil - eHealthMe. Plaquenil is a prescription medication used to reduce pain and swelling caused by diseases of the immune system such as rheumatoid arthritis, juvenile arthritis, and systemic lupus erythematosus SLE. This medication belongs to a group of drugs called DMARDs disease modifying antirheumatic drugs which work by suppressing the excessive activity of the immune system. Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. And of greater importance, Plaquenil has less systemic side effects than other drugs used for lupus, so there is a real advantage in using it as long as one can.