Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Extinction coefficient chloroquine phosphate Plaquenil retina toxicity I have been allergic to sulfa meds for over 30 years. I have been taking plaquenil for about 8 years with no problems. However, I was givin the generic Plaquenil at first, and I did have a reaction to that - until now I didn't reliese was the same as my sulfa reaction. These are not sulfates. Sulfate used after a drug name is just the last name of the chemical, its the sulfate salt. It has nothing to do with sulfonamides. Allergy to sulfonamide antibiotics has no relationship to allergies to hydroxychloroquine. I did accidentally take a sulfa drug about 5 years ago and still had the horrible reaction so know I'm still allergic even while being on plaquenil. I also take meloxicam which is in the same family as celebrex and have no problem. I would definitely look for another opinion as plaquenil was a lifesave when I first was diagnosed and it has relatively low side effects. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Is plaquenil a sulfa drug Plaquenil and Sulfa Allergies" Lupus Community - Support Group, Is hydroxychloroquine Sulfate a member of the sulfa drug. Plaquenil and chronic fatigueMylan hydroxychloroquine side effectsHydroxychloroquine vs chloroquineHydroxychloroquine tonic waterWhat kind of medicine is mefloquine chloroquine primaquine and quinine PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Plaquenil Hydroxychloroquine Sulfate. Plaquenil when allergic to sulfa? Lupus Forums at. Sulfasalazine - Medications for Rheumatoid. Hydroxychloroquine sulfate Plaquenil is not a sulfa drug. That is a misconception. However, hydroxychloroquine can be associated with serious dermatological side effects including severe rashes. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. Plaquenil is most often well-tolerated but, like with any drug, side effects are possible. Most people about 90% who take antimalarial medications experience no side effects. If common side effects do occur, they are usually minor and last only for a short period of time.