Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine suicide Weiggt gain tryibg to get off plaquenil Hydroxychloroquine retinopathy and night vision Hyperpigmentation is a dermatological condition when the getting discoloured and darkened in places. It is mainly caused due to the overproduction of melanin, the pigment that gives skin its. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of. Home August 2013 - Volume 19 - Issue 5 Hydroxychloroquine-Induced Hyperpigmentation. Log in to view full text. If you're not a subscriber, you can You can read the full text of this article if you-- Select an option -- Log In Buy This Article Become a Subscriber Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hyperpigmentation plaquenil Will you have Skin discoloration - bluish with Plaquenil., Hydroxychloroquine DermNet NZ Chloroquine dosage for malaria prevention Drug-Induced Hyperpigmentation caused by Plaquenil Hydroxychloroquine Plaquenil Hydroxycholoroquine Side Effects. Dermatologic side effects have included mucocutaneous hyperpigmentation, nonlight-sensitive psoriasis, bleaching of hair, alopecia, pruritus, photosensitivity, and skin eruptions such as urticarial, morbilliform, lichenoid, maculopapular, purpuric, erythema annulare centrifugum, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, and exfoliative dermatitis. Systemic Scleroderma Skin Involvement Hyperpigmentation.. Hydroxychloroquine-Induced Hyperpigmentation JCR.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine is an antimalarial medication that can cause hyperpigmentation of nails, mucosa, and skin 1–5. Retrospective studies cite the incidence of drug-related hyperpigmentation from hydroxychloroquine to be as high as 33% of individuals. Elder abuse is a cause of significant morbidity and mortality in older individuals 7–9. I believe this has been mentioned a while back, but thought I'd ask again who has gotten small brown spots on their skin after sun exposure? I've been on Plaquenil about 2 months, and it has helped my knee/back pain, which is wonderful! Skin hyperpigmentation is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Omniscan, and have Arteriogram.