Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Plaquenil arthritis meds Plaquenil and radiotherapy Plaquenil worse before better reddit Plaquenil and cholesterol Every facet of Customer Care at ZEISS is designed to protect your investment in your equipment. Whether it is a high-end surgical microscope, an ophthalmic laser, diagnostic equipment, or radiotherapy system, we provide timely, responsive services through a national network of highly skilled technicians. Today it is recommended that every single person on Plaquenil get a visual field 10-2 test, plus one of the three other highly sensitive screening tests the FAF fundus autofluorescence imaging, the SD-OCT spectral domain optical coherence, or the multifocal electroretinogram mfERG,” Thomas says. A 45-year-old black female presented with no ocular or visual complaints. Her ocular history was unremarkable. However, her medical history was significant for a recent diagnosis of lupus. Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil hydroxychloroquine, Sanofi-Aventis therapy. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil visual field Plaquenil therapy and eye exams. - Eye Care - MedHelp, Protecting your eyesight when taking Plaquenil Lupus Foundation of. Chloroquine phosphate shelf life Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Protecting your eyesight when taking Plaquenil Lupus.. New Plaquenil Guidelines -. Plaquenil Side Effects on Your Eyes and Vision. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Visual field abnormalities occurred in 35 patients. Five patients developed hydroxychloroquine ocular adverse effects, of which 4 were visual field defects and 1 was significant vortex keratopathy. None of these patients developed visual symptoms, changes in visual acuity, or fundus abnormalities resulting from drug toxic effects nor did they. It has become fairly common practice for most rheumatologists to recommend that patients being treated with hydroxychloroquine be seen for formal visual field evaluation once or twice a year to monitor for retinal toxicity. The previous AAO guideline recommended screening every 12 months.