Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil acetaminophen interaction Chloroquine method of action lysosome How common is chloroquine retinopathy Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Just wondering if anyone else had problems with loss of appetite and weight loss while on plaquenil. I had my dose increased to 400mg a day about three weeks ago, and since then I have no appetite whatsoever. Weight is falling off me at a rather alarming rate - at least half a stone a week. Increased Appetite is #184 concern in Plaquenil discussions. Plaquenil is an arthritis medication and an anti infectious agent. Uses Plaquenil is prescribed for Lupus, RA, Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil increased appetite Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, Plaquenil & weight loss Lupus Forums at The Lupus Site Plaquenil method of actionGoodrx hydroxychloroquineRenault's disease hydroxychloroquineHydroxychloroquine plaque psoriasis RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Common and Rare Side Effects for Plaquenil Oral. Can Plaquenil cause Increased Appetite? - Treato. PLAQUENIL Side Effects, Reviews by Patients -. I started to take plaquenil for my mild lupus about 3 weeks ago and I noticed that I am having less appetite these days. I get hungry during dinner time, but all the foods does not taste as good as before. It feels weird! Eating delicious food was one of the joy of my life. The food that I used to love does not taste as good as before. humm. Combining telbivudine Tyzeka and hydroxychloroquine may increase the risk of unexplained muscle pain, tenderness, or weakness because both drugs cause such side effects. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines. Chlortetracycline has been used in livestock agriculture to promote growth through increased food intake, weight gain, and improved herd health 11. Since the 1940s, tetracyclines have been associated with weight gain in human infants and children 12, and one study showed significant weight gain in adults 13.