Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Precautions of chloroquine Plaquenil throat pain Hydroxyzine chloroquine Mg/kg base not to exceed 400 mg 310 mg base PO weekly, starting 2 weeks before exposure and continued for 4 weeks after departure from area With prolonged therapy, obtain CBCs periodically. Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day 200 bid. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Dosage of plaquenil Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Plaquenil Uses, Dosage & Side Effects - Does plaquenil lead to kidney failurePlaquenil and glutamateHow to take plaquenil 200 mg Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. Your doctor may gradually increase or decrease your dosage over time to find the right levels for your specific symptoms and needs while having the least amount of negative side effects. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Plaquenil Risk Calculators. Plaquenil Oral Uses, Side Effects, Interactions.. Melton & Thomas describe the typical safe Plaquenil dosage this way The usual dosage is two 200mg tablets per day. This is generally a "safe" dose for patients having a lean body weight of at least 135 lbs. The generally-regarded safe dosage is 6.5mg/kg/qd, thus the 135 lb. safety threshold. Typical starting dose is 800 mg. This is followed by 400 mg three times 6 hours after the first dose, 24 hours after the first dose, and 48 hours after the first dose. Treatment of Uncomplicated Malaria Adults 800 mg 620 mg base followed by 400 mg 310 mg base at 6 hours, 24 hours and 48 hours after the initial dose total 2000 mg hydroxychloroquine sulfate or 1550 mg base.