It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the Web MD Site. Chloroquine rheumatoid arthritis mechanism of action Sam's club pharmacy hydrochloride hydroxychloroquine Mechanism of chloroquine resistance Chloroquine lysosome fusion Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Here are the three most common antimalarial drugs prescribed for lupus Hydroxychloroquine Plaquenil This is the most commonly prescribed antimalarial. Chloroquine Aralen This drug has been known to have more serious side effects. Quinacrine Atabrine Quinacrine is another. Hydroxychloroquine is used for its effect on systemic lupus erythematosus SLE disease activity and long-term benefits. This can be limited by adherence. One way to assess adherence is to measure blood levels. Conflicting data exist regarding blood levels. The following information is NOT intended to endorse any particular medication. If you think you may have a medical emergency, immediately call your doctor or dial 911. Is plaquenil best for lupus Hydroxychloroquine in systemic lupus erythematosus SLE., Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Plaquenil 200mg buyPlaquenil and reduced renal function Plaquenil Hydroxychloroquine. The drug of choice for systemic lupus erythematosus SLE or "Lupus" and rheumatoid arthritis. Hydroxychloroquine is a one of a number of drugs which have been used for many years in the treatment of malaria. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases. Plaquenil. A medication for Lupus. Hydroxychloroquine Blood Levels in SLE Clarifying dosing.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Dooley says time of day also matters less with Plaquenil® hydroxychloroquine. But, it’s best taken with food. Non-steroidal anti-inflammatories like ibuprofen and naproxen can give people heartburn or upset stomach, she says, so take them at least two hours before you lie down at night or with medications that protect your stomach. For best results, keep using the medication as directed. Talk with your doctor if you have fever, vomiting, or diarrhea during your treatment. When treating lupus or arthritis, Plaquenil is usually given daily for several weeks or months. For best results, keep using the medication as directed. Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. This drug is also effective at preventing lupus flares.