Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Chloroquine alcohol use What does plaquenil do to your eyes Rates of plaquenil toxicity Plaquenil for fibromyalgia What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. If you are taking hydroxychloroquine over a long duration, it is important to take eye exams every 6 to 12 months. 6 Do not take hydroxychloroquine if you experience vision symptoms, including problems seeing or reading, light sensitivity, blurred distance vision, or light flashes or streaks. 5 What is Hydroxychloroquine, and What Does It Do? According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with can also reduce the incidence of joint damage, thus lessening the risk of developing a long-term disability from complications. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. How long to take plaquenil Plaquenil.long do I have to wait? DailyStrength, Hydroxychloroquine Plaquenil - Plaquenil depressionPlaquenil araHydroxychloroquine rosaceaHydroxychloroquine sulfate discount cardChloroquine clinical trials cancer Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions.. RA and Hydroxychloroquine How Effective is it for.. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Take Plaquenil exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. especially if you take it for a. Donald E. Thomas Jr. MD, FACR, FACP, a practicing rheumatologist in Greenbelt, Md. and author of The Lupus Encyclopedia, regularly prescribes Plaquenil to his lupus patients. “We know that people with lupus who take their Plaquenil regularly are much more likely to live a long, normal life compared with those who don’t,” he says.